Trends in Cell Biology

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08.10.2021

Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis

Authors Lavdovskaia E, Hillen HS, Richter-Dennerlein R Journal Trends in Cell Biology Citation Trends Cell Biol. 2021. Abstract Final maturation steps during ribo-some biogenesis require the assis-tance of assembly and qualitycontrol factors to ensure the foldingof rRNA and proteins into a func-tional translation machinery. Herewe integrate several recent struc-tural snapshots
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14.01.2021

Phase Separation during Germline Development

Authors So C, Cheng S, Schuh M Journal Trends in Cell Biology Citation Trends in Cell Biology, Jan 2021, online. Abstract Phase separation has emerged as a new key principle of intracellular organization. Phase-separated structures play diverse roles in various biological processes and pathogenesis of protein aggregation diseases. Recent work
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05.01.2021

Role of GTPases in Driving Mitoribosome Assembly

Authors Maiti P, Lavdovskaia E, Barrientos A, Richter-Dennerlein R Journal Trends in Cell Biology Citation Trends Cell Biol. 2021 Jan 5:S0962-8924(20)30254-3. Abstract Mitoribosomes catalyze essential protein synthesis within mitochondria. Mitoribosome biogenesis is assisted by an increasing number of assembly factors, among which guanosine triphosphate hydrolases (GTPases) are the most abundant
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01.12.2020

Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells

Authors Bäuerlein FJB, Fernandez-Busnadiego R, Baumeister W Journal Trends in Cell Biology Citation Trends Cell Biol. 2020 Dec;30(12):951-966. Abstract Neurodegenerative diseases affect the lives of millions of people across the world, being particularly prevalent in the aging population. Despite huge research efforts, conclusive insights into the disease mechanisms are still
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