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01.09.2021

The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1

Authors Sadredini M, Manotheepan R, Lehnart SE, Anderson ME, Sjaastad I, Stokke MK Journal Physiological Reports Citation Physiol Rep. 2021 Sep;9(18):e15030. Abstract Catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) is an inherited arrhythmogenic disorder caused by missense mutations in the cardiac ryanodine receptors (RyR2), that result in increased β-adrenoceptor stimulation-induced
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