Nature

Authors Jebran AF, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, Ensminger S, Bremmer F, Moussavi A, Yang H, Qin X, Mißbach S, Drummer C, Baraki H, Boretius S, Hasenauer C, Nette T, Kowallick J, Ritter CO, Lotz J, Didié M, Mietsch M, Meyer T, Kensah G, Krüger

Authors Karamanlis D, Khani MH, Schreyer HM, Zapp SJ, Mietsch M, Gollisch T Journal Nature Citation Nature. 2024 Nov 20. Abstract The role of the vertebrate retina in early vision is generally described by the efficient coding hypothesis1,2, which predicts that the retina reduces the redundancy inherent in natural scenes3

Authors Wagner J, Carvajal AI, Bracher A, Beck F, Wan W, Bohn S, Körner R, Baumeister W, Fernandez-Busnadiego R, Hartl FU Journal Nature Citation Nature. 2024 Aug 21. Abstract Chaperonins are large barrel-shaped complexes that mediate ATP-dependent protein folding1-3. The bacterial chaperonin GroEL forms juxtaposed rings that bind unfolded protein

Authors Fianu I, Ochmann M, Walshe JL, Dybkov O, Cruz JN, Urlaub H, Cramer P   Journal Nature   Citation Nature. 2024 Apr 3.   Abstract The Integrator complex can terminate RNA polymerase II (Pol II) in the promoter-proximal region of genes. Previous work has shed light on how Integrator

Authors Jovasevic V, Wood EM, Cicvaric A, Zhang H, Petrovic Z, Carboncino A, Parker KK, Bassett TE, Moltesen M, Yamawaki N, Login H, Kalucka J, Sananbenesi F, Zhang X, Fischer A, Radulovic J   Journal Nature   Citation Nature. 2024 Apr;628(8006):145-153.   Abstract As hippocampal neurons respond to diverse types

Authors Wolfram-Schauerte M, Pozhydaieva N, Grawenhoff J, Welp LM, Silbern I, Wulf A, Billau FA, Glatter T, Urlaub H, Jäschke A, Höfer K Journal Nature Citation Nature. 2023 Aug 16. Abstract The mechanisms by which viruses hijack the genetic machinery of the cells they infect are of current interest. When

Authors Schmitzová J, Cretu C, Dienemann C, Urlaub H, Pena V Journal Nature Citation Nature. 2023 May 10. Abstract Pre-mRNA splicing follows a pathway driven by ATP-dependent RNA helicases. A crucial event of the splicing pathway is the catalytic activation, which takes place at the transition between the activated Bact

Authors Kosmidis E, Shuttle CG, Preobraschenski J, Ganzella M, Johnson PJ, Veshaguri S, Holmkvist J, Møller MP, Marantos O, Marcoline F, Grabe M, Pedersen JL, Jahn R, Stamou D Journal Nature Citation Nature. 2022 Nov;611(7937):827-834. Abstract Vacuolar-type adenosine triphosphatases (V-ATPases)1,2,3 are electrogenic rotary mechanoenzymes structurally related to F-type ATP synthases4,5.

Authors Kokic G, Wagner FR, Chernev A, Urlaub H, Cramer P Journal Nature Citation Nature 2021 Abstract Transcription-coupled DNA repair removes bulky DNA lesions from the genome and protects cells against ultraviolet (UV) irradiation. Transcription-coupled DNA repair begins when RNA polymerase II (Pol II) stalls at a DNA lesion and recruits

Authors Aibara S, Schilbach S, Cramer P Journal Nature Citation Nature. 2021 Apr 26. Abstract The initiation of transcription is a focal point for the regulation of gene activity during mammalian cell differentiation and development. To initiate transcription, RNA polymerase II (Pol II) assembles with general transcription factors into a