Journal of Cell Biology

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18.12.2024

A proteome-wide yeast degron collection for the dynamic study of protein function

Authors Valenti R, David Y, Edilbi D, Dubreuil B, Boshnakovska A, Asraf Y, Salame TM, Sass E, Rehling P, Schuldiner M Journal Journal of Cell Biology Citation J Cell Biol. 2025 Feb 3;224(2):e202409050. Abstract Genome-wide collections of yeast strains, known as libraries, revolutionized the way systematic studies are carried out.
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30.11.2023

Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity

Authors Altas B, Rhee HJ, Ju A, Solís HC, Karaca S, Winchenbach J, Kaplan-Arabaci O, Schwark M, Ambrozkiewicz MC, Lee C, Spieth L, Wieser GL, Chaugule VK, Majoul I, Hassan MA, Goel R, Wojcik SM, Koganezawa N, Hanamura K, Rotin D, Pichler A, Mitkovski M, de Hoz L, Poulopoulos A,
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06.06.2022

Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway

Authors Farkas Á, Urlaub H, Bohnsack KE, Schwappach B Journal Journal of Cell Biology Citation J Cell Biol. 2022 Jun 6;221(6):e202201036. Abstract The guided entry of tail-anchored proteins (GET) pathway targets C-terminally anchored transmembrane proteins and protects cells from lipotoxicity. Here, we reveal perturbed ergosterol production in ∆get3 cells and
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25.10.2021

Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels

Authors Eisenberg-Bord M, Zung N, Collado J, Drwesh L, Fenech EJ, Fadel A, Dezorella N, Bykov YS, Rapaport D, Fernandez-Busnadiego R, Schuldiner M Journal Journal of Cell Biology Citation J Cell Biol. 2021 Nov 1;220(11):e202104100. Abstract Mitochondrial functions are tightly regulated by nuclear activity, requiring extensive communication between these organelles.
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07.10.2019

Dynamic instability of clathrin assembly provides proofreading control for endocytosis

Authors Chen Y, Yong J, Martinez-Sanchez A, Yang Y, Wu Y, De Camilli P, Fernandez-Busnadiego R, Wu M Journal Journal of Cell Biology Citation J Cell Biol. 2019 Oct 7;218(10):3200-3211. Abstract Clathrin-mediated endocytosis depends on the formation of functional clathrin-coated pits that recruit cargos and mediate the uptake of those
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