Journal of Cell Biology

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Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway

Authors Farkas Á, Urlaub H, Bohnsack KE, Schwappach B Journal Journal of Cell Biology Citation J Cell Biol. 2022 Jun 6;221(6):e202201036. Abstract The guided entry of tail-anchored proteins (GET) pathway targets C-terminally anchored transmembrane proteins and protects cells from lipotoxicity. Here, we reveal perturbed ergosterol production in ∆get3 cells and
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Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels

Authors Eisenberg-Bord M, Zung N, Collado J, Drwesh L, Fenech EJ, Fadel A, Dezorella N, Bykov YS, Rapaport D, Fernandez-Busnadiego R, Schuldiner M Journal Journal of Cell Biology Citation J Cell Biol. 2021 Nov 1;220(11):e202104100. Abstract Mitochondrial functions are tightly regulated by nuclear activity, requiring extensive communication between these organelles.
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Dynamic instability of clathrin assembly provides proofreading control for endocytosis

Authors Chen Y, Yong J, Martinez-Sanchez A, Yang Y, Wu Y, De Camilli P, Fernandez-Busnadiego R, Wu M Journal Journal of Cell Biology Citation J Cell Biol. 2019 Oct 7;218(10):3200-3211. Abstract Clathrin-mediated endocytosis depends on the formation of functional clathrin-coated pits that recruit cargos and mediate the uptake of those
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