Frontiers in Physiology

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24.01.2024

Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions

Authors Bloothooft M, Verbruggen B, Seibertz F, van der Heyden MAG, Voigt N, de Boer TP Journal Frontiers in Physiology Citation Front Physiol. 2024 Jan 24;15:1298340. Abstract Background: The rapid delayed rectifier potassium current (IKr) is important for cardiac repolarization and is most often involved in drug-induced arrhythmias. However, accurately
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11.10.2022

Editorial: Cardiac optogenetics: Using light to observe and excite the heart

Authors Bruegmann T, Smith GL, Lehnart SE Journal Frontiers in Physiology Citation Front Physiol. 2022 Oct 11;13:1031062. Abstract No abstract available. DOI 10.3389/fphys.2022.1031062   Pubmed Link  
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10.03.2022

A mathematical model for electrical activity in pig atrial tissue

Authors Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R Journal Frontiers in Physiology Citation Front Physiol. 2022 Mar 10;13:812535. Abstract State of the art mathematical models are currently used to bridge the gap between basic research conducted in the laboratory and preclinical research conducted on large
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09.12.2021

The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool

Authors Wegener JW, Wagdi A, Wagner E, Katschinski DM, Hasenfuss G, Bruegmann T, Lehnart SE Journal Frontiers in Physiology Citation Front Physiol. 2021 Dec 9;12:777770. Abstract Missense mutations in the cardiac ryanodine receptor type 2 (RyR2) characteristically cause catecholaminergic arrhythmias. Reminiscent of the phenotype in patients, RyR2-R2474S knockin mice develop
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18.11.2021

Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review

Authors Müllenbroich MC, Kelly A, Acker C, Bub G, Bruegmann T, Di Bona A, Entcheva E, Ferrantini C, Kohl P, Lehnart SE, Mongillo M, Parmeggiani C, Richter C, Sasse P, Zaglia T, Sacconi L, Smith GL Journal Frontiers in Physiology Citation Front Physiol. 2021 Nov 18;12:769586. Abstract Optical techniques for
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