EBioMedicine

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01.06.2022

Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial

Authors Levin J, Sing N, Melbourne S, Morgan A, Mariner C, Spillantini MG, Wegrzynowicz M, Dalley JW, Langer S, Ryazanov S, Leonov A, Griesinger C, Schmidt F, Weckbecker D, Prager K, Matthias T, Giese A Journal eBioMedicine Citation EBioMedicine. 2022 Jun;80:104021 Abstract Background: Synucleinopathies such as Parkinson ́ s disease
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07.01.2021

Understanding and treating paediatric hearing impairment

Authors Wrobel C, Zafeiriou MP, Moser T Journal EBioMedicine Citation EBioMedicine. 2021 Jan 7;63:103171. Abstract Sensorineural hearing impairment is the most frequent form of hearing impairment affecting 1–2 in 1000 newborns and another 1 in 1000 adolescents. More than 50% of congenital hearing impairment is of genetic origin and some
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