Acta Neuropathologica

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29.08.2024

PRDM16-DT is a novel lncRNA that regulates astrocyte function in Alzheimer’s disease

Authors Schröder S, Fuchs U, Gisa V, Pena T, Krüger DM, Hempel N, Burkhardt S, Salinas G, Schütz AL, Delalle I, Sananbenesi F, Fischer A Journal Acta Neuropahologica Citation Acta Neuropathol. 2024 Aug 29;148(1):32. Abstract Astrocytes provide crucial support for neurons, contributing to synaptogenesis, synaptic maintenance, and neurotransmitter recycling. Under
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08.07.2023

More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy

Authors Flores-Leon M, Outeiro TF Journal Acta Neuropathologica Citation Acta Neuropathol. 2023 Jul 8. Abstract The accumulation of proteinaceous inclusions in the brain is a common feature among neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease (PD), and dementia with Lewy bodies (DLB). The main neuropathological hallmark of PD and
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24.02.2021

Emerging concepts in synucleinopathies

Authors Outeiro TF Journal Acta Neuropathologica (Editorial) Citation Acta Neuropathol. 2021 Feb 24. Abstract No abstract available DOI 10.1007/s00401-021-02290-7 Pubmed Link  
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30.01.2021

Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

Authors Erskine D, Koss D, Korolchuk VI, Outeiro TF, Attems J, McKeith I Journal Acta Neuropathologica Citation Acta Neuropathol. 2021 Jan 30. Abstract Accumulation of the protein α-synuclein into insoluble intracellular deposits termed Lewy bodies (LBs) is the characteristic neuropathological feature of LB diseases, such as Parkinson’s disease (PD), Parkinson’s
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19.10.2020

MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis

Authors Wildemann B, Jarius S, Franz J, Ruprecht K, Reindl M, Stadelmann C Journal Acta Neuropathologica Citation Acta Neuropathol. 2020 Oct 19. Abstract no abstract available DOI 10.1007/s00401-020-02236-5 Pubmed Link  
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31.05.2019

Depopulation of dense alpha-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model

Authors Wegrzynowicz, M.Bar-On D, Calo L, Anichtchik O, Iovino M, Xia J, Ryazanov S, Leonov A, Giese A, Dalley JW, Griesinger C, Ashery U, Spillantini MG Journal Acta Neuropathologica Citation Acta Neuropathol. 2019 Oct;138(4):575-595. Abstract Parkinson’s disease (PD) is characterized by the presence of α-synuclein aggregates known as Lewy bodies
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