Zelarayan-Behrend, Laura

Authors Kim R, Nagel SH, Liaw NY, Zimmermann WH, Zelarayan LC, Schoger E Journal Stem Cell Research Citation Stem Cell Research (2024). Abstract The fluorescence ubiquitination cell cycle inhibitor (FUCCI) has been introduced to monitor cell cycle activity in living cells, including human induced pluripotent stem cells (hiPSC) and derived

Authors Knauer C, Haltern H, Schoger E, Kügler S, Roos L, Zelarayán LC, Hasenfuss G, Zimmermann WH, Wollnik B, Cyganek L Journal Molecular Therapy: Nucleic Acids Citation Mol Ther Nucleic Acids. 2024 Jan 23;35(1):102123. Abstract Gene variants in LZTR1 are implicated to cause Noonan syndrome associated with a severe and

Authors Priesmeier L, Schoger E, Cyganek L, Zelarayán LC Journal Stem Cell Research Citation Stem Cell Res. 2023 Jul 5;71:103163. Abstract Towards increasing the possibility for temporal control of gene expression using CRISPR activation (a) systems, we generated homozygous human induced pluripotent stem cell (hiPSC) lines carrying a doxycycline (dox)-inducible

Authors Schoger E, Bleckwedel F, Germena G, Rocha C, Tucholla P, Sobitov I, Möbius W, Sitte M, Lenz C, Samak M, Hinkel R, Varga ZV, Giricz Z, Salinas G, Gross JC, Zelarayán LC Journal Communications Biology Citation Commun Biol. 2023 Jan 21;6(1):79. Abstract Aberrant Wnt activation has been reported in failing

Authors Shomroni O, Sitte M, Schmidt J, Parbin S, Ludewig F, Yigit G, Zelarayan LC, Streckfuss-Bömeke K, Wollnik B, Salinas G Journal Scientific Reports Citation Sci Rep. 2022 Mar 8;12(1):4091. Abstract Single cell multi-omics analysis has the potential to yield a comprehensive understanding of the cellular events that underlie the

Authors Schoger E, Lelek S, Panáková D, Zelarayán LC Journal Frontiers in Cardiovascular Medicine Citation Front Cardiovasc Med. 2022 Jan 14;8:783072. Abstract Molecular and genetic differences between individual cells within tissues underlie cellular heterogeneities defining organ physiology and function in homeostasis as well as in disease states. Transcriptional control of

Authors Zelarayan L, Vendrell V, Domínguez-Frutos E, López-Hernández I, Schimmang-Alonso K, Alonso MT, Alvarez Y, Maier H, Anderson MJ, Lewandoski M, Schimmang T. Journal Developmental Dynamics Citation Dev Dyn. 2021 Oct 31. Abstract Background Fibroblast growth factors (Fgfs) are required for survival and organ formation during embryogenesis. Fgfs often execute