Huisken, Jan

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21.02.2025

Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue

Authors Aakhte M, Mueller GF, Li J, Weiss KR, Roos L, Diniz AM, Wenzel J, Schwaninger M, Moser T, Huisken J Journal BioRxiv Citation bioRxiv 2025.02.21.639411. Abstract Light sheet microscopy is the ideal technique for multiscale imaging of large and cleared tissues, and it is desirable to achieve the highest
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23.01.2025

Leonardo: A Toolset to Remove Sample-Induced Aberrations in Light Sheet Microscopy Images

Authors Liu Y, Müller G, Kowitz L, Chobola T, Weiss K, Maier P, Luo J, Roeßing M, Stenzel M, Grüneboom A, Paetzold J, Ertürk A, Navab N, Marr C, Chen J, Huisken J, Peng T Journal Research Square Citation Research Square 2025. Abstract Selective plane illumination microscopy (SPIM, also known
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31.08.2024

The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish

Authors Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F Journal Nature Communications Citation Nat Commun. 2024 Aug 31;15(1):7589. Abstract The contribution of endocardial cells (EdCs) to the
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06.06.2024

Open Problem: Active Representation Learning

Authors Milosevic N, Müller G, Huisken J, Scherf N Journal Arxiv Citation arXiv:2406.03845. Abstract In this work, we introduce the concept of Active Representation Learning, a novel class of problems that intertwines exploration and representation learning within partially observable environments. We extend ideas from Active Simultaneous Localization and Mapping (active
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04.01.2024

Image restoration of degraded time-lapse microscopy data mediated by near-infrared imaging

Authors Gritti N, Power RM, Graves A, Huisken J Journal Nature Methods Citation Nat Methods (2024). Abstract Time-lapse fluorescence microscopy is key to unraveling biological development and function; however, living systems, by their nature, permit only limited interrogation and contain untapped information that can only be captured by more invasive
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