Bäuerlein, Felix J.B.

Authors Zhao DY, Bäuerlein FJB, Saha I, Hartl FU, Baumeister W, Wilfling F Journal Molecular Cell Citation Mol Cell. 2024 May 16;84(10):1980-1994.e8. Abstract Aggregation of proteins containing expanded polyglutamine (polyQ) repeats is the cytopathologic hallmark of a group of dominantly inherited neurodegenerative diseases, including Huntington’s disease (HD). Huntingtin (Htt), the

Authors Bäuerlein FJB, Baumeister W Journal Journal of Molecular Biology Citation J Mol Biol. 2021 Aug 9:167187. Abstract Traditionally, structural biologists approach the complexity of cellular proteomes in a reductionist manner. Proteomes are fractionated, their molecular components purified and studied one-by-one using the experimental methods for structure determination at their