01.07.2021
The German Physical Society (Deutsche Physikalische Gesellschaft, DPG) awards the “Medaille für naturwissenschaftliche Publizistik 2021” to MBExC member Viola Priesemann. The DPG thereby recognizes her exceptional commitment regarding science communication and advice of scientists and politics in the context of Covid-19 pandemic. Link to the German Physical Society press release
29.06.2021
Research, construction, COVID-19: Lower Saxony’s Minister President Stephan Weil visits UMG
Stephan Weil, Minister President of Lower Saxony, visited the University Medical Center Göttingen (UMG) to learn more about the planned UMG constructions, cutting-edge research, and to assess the Corona situation at the UMG and in Lower Saxony. Together with Dr. Gabriele Andretta, Speaker of the State Parliament in Lower Saxony,
27.06.2021
Brain iron enrichment attenuates α-synuclein spreading after injection of preformed fibrils
Authors Joppe KDN, Tatenhorst L, Caldi Gomes L, Zhang S, Parvaz M, Carboni E, Roser AE, El DeBakey H, Bähr M, Vogel-Mikuš K, Ip CW, Becker S, Zweckstetter M, Lingor P Journal Journal of Neurochemistry Citation J Neurochem. 2021 Jun 27. Abstract Regional iron accumulation and α-synuclein (α-syn) spreading pathology
25.06.2021
New Max Planck Institute of Multidisciplinary Sciences
The Max Planck Institutes (MPI) for Biophysical Chemistry and for Experimental Medicine will merge to the new Max Planck Institue of Multidisciplinary Sciences. The decision-making bodies of the Max Planck Society (MPS) approved the plan submitted by the two institutes on March 12. Formally, both institutions will be closed and
25.06.2021
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state
Authors Yigit G, Sheffer R, Daana M, Li Y, Kaygusuz E, Mor-Shakad H, Altmüller J, Nürnberg P, Douiev L, Kaulfuss S, Burfeind P, Wollnik B, Brockmann K Journal Journal of Medical Genetics Citation J Med Genet. 2021 Jun 25:jmedgenet-2021-107769. Abstract Background Developmental and epileptic encephalopathies (DEEs) represent a group of
24.06.2021
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines
Authors Helm MS, Dankovich TM, Mandad S, Rammer B, Jähne S, Salimi V, Koerbs C, Leibrandt R, Urlaub H, Schikorski T, Rizzoli SO Journal Nature Neuroscience Citation Nat Neurosci (2021). Abstract Dendritic spines, the postsynaptic compartments of excitatory neurotransmission, have different shapes classified from ‘stubby’ to ‘mushroom-like’. Whereas mushroom spines
24.06.2021
Photophysical properties and fluorescence lifetime imaging of exfoliated near-infrared fluorescent silicate nanosheets
Authors Selvaggio G, Weitzel M, Oleksiievets N, Oswald TA, Nißler R, Mey I, Karius V, Enderlein J, Tsukanov R, Kruss S Journal Nanoscale Advances Citation Nanoscale Adv., 2021. Abstract The layered silicates Egyptian Blue (CaCuSi4O10, EB), Han Blue (BaCuSi4O10, HB) and Han Purple (BaCuSi2O6, HP) emit as bulk materials bright
17.06.2021
Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo
Authors Žumer K, Maier KC, Farnung L, Jaeger MG, Rus P, Winter G, Cramer P Journal Molecular Cell Citation Mol Cell. 2021 Jun 17:S1097-2765(21)00441-X. In press. Abstract Transcription by RNA polymerase II (RNA Pol II) relies on the elongation factors PAF1 complex (PAF), RTF1, and SPT6. Here, we use rapid
17.06.2021
Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis
Authors Bergner CG, Genc N, Hametner S, Franz J, van der Meer F, Mitkovski M, Weber MS, Stoltenburg-Didinger G, Kühl JS, Köhler W, Brück W, Gärtner J, Stadelmann-Nessler C Journal Glia Citation Glia, 2021, 1-16. Abstract Cerebral disease manifestation occurs in about two thirds of males with X-linked adrenoleukodystrophy (CALD)
16.06.2021
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling
Authors Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R Journal Nature Communications Citation Nat Commun. 2021 Jun 16;12(1):3672. Abstract Ribosome biogenesis requires auxiliary factors to promote folding and assembly of ribosomal proteins and RNA. Particularly, maturation of the peptidyl transferase center (PTC)





